February 22, 2024


The European Medicines Agency started investigating the issue in July. (Representational)

The European Union’s drugs regulator has asked pharma companies including Novo Nordisk A/S and Eli Lilly & Co. for more information as it reviews the potential risk of suicidal thoughts associated with a new class of weight-loss medicines.

The European Medicines Agency started investigating the issue in July after reports of suicidal thoughts and self-harm from people who had been taking the anti-obesity drugs. The review is focused on so-called GLP-1 treatments, a class that includes Novo’s Wegovy weight-loss shot as well as its diabetes medicine Ozempic. The drugs are among the hottest sellers in pharma.

In a statement Friday, the EMA’s safety committee said it had reviewed all clinical trial evidence and published literature on the subject, adding: “While at this point no conclusion can be drawn on a causal association, there are several issues that still need to be clarified.”

The committee has agreed further lists of questions to be addressed by the makers of these medicines and said it will discuss the topic again at its meeting in April.

Though their use for weight loss is comparatively recent, GLP-1 drugs have a more than 15-year history as treatments for diabetes. The EMA investigation also includes dulaglutide, the active ingredient in Lilly’s diabetes medicine Trulicity, and AstraZeneca Plc’s diabetes drug Byetta.

“Patient safety is Lilly’s top priority,” a spokesperson for the company told Bloomberg Friday. “We will continue to respond to the regulatory reviews regarding safety signals related to dulaglutide as part of our routine regulatory review processes.”

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)



Source link

Leave a Reply

Your email address will not be published. Required fields are marked *

Batman138 Bro138 Dolar138 Gas138 Gudang138 Hoki99 Ligaciputra Panen77 Zeus138 Kilat77 Planet88 Gaspol168 Sikat88 Rupiah138 Garuda138 Gacor77 Roma77 Sensa138 Panen138 Slot138 Gaco88 Elanggame Candy99 Cair77 Max7 Best188 Space77 Sky77 Luxury777 Maxwin138 Bosswin168 Cocol88 Slot5000 Babe138 Luxury138 Jet77 Bonanza138 Bos88 Aquaslot Taktik88 Lord88 Indobet Slot69 Paus138 Tiktok88 Panengg Bingo4d Stars77 77dragon Warung168 Receh88 Online138 Tambang88 Asia77 Klik4d Bdslot88 Gajah138 Bigwin138 Markas138 Yuk69 Emas168 Key4d Harta138  Gopek178 Imbaslot Imbajp Deluna4d Luxury333 Pentaslot Luxury111 Cair77 Gboslot Pandora188 Olxtoto Slotvip Eslot Kuy138 Imbagacor Bimabet